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While one of the trials evaluated Orforglipron versus Dapagliflozin in 962 patients with type-2 diabetes inadequately controlled on Metformin, the other trial assessed Orforglipron versus placebo in 546 adults with type 2 diabetes and inadequate glycemic control with titrated insulin glargine

From Matt Levine: A few months ago, someone told me that they had heard a rumor that a bank or hedge fund had banned its traders from taking Ozempic, Wegovy and other GLP-1 weight-loss drugs

Common infections such as syphilis, chancroid, and lymphogranuloma venereum frequently lead to groin lymph node swelling

PLoS ONE 14 , e0212992 (2019)

Complementing GLP-1 medications like semaglutide or tirzepatide

Enzyme inactivation is not the only mechanism by which reactive electrophilic analogues of glutathione, such as EdAG, can elicit, disturb or disrupt biological mechanisms