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Jason Clark Director of Special Markets Jason Clark joined KLOwen as the Director of Special Markets in February 2023

GLP-1 receptor agonists are not new drugs

72 Our team used palmitic acid stimulation to induce neuronal IR, confirming that ER stress is involved in the functional damage of neurons induced by IR, and exendin significantly alleviates both ER stress and neuronal damage (data not shown)

After this initial month, healthcare providers typically increase the dose in 2.5 mg increments every four weeks, up to a maximum maintenance dose of 15 mg, depending on patient tolerance and individual weight loss goals