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Uppal H, Zhai Y, Gangopadhyay A, Khadem S, Ren S, Moser JA, Xie W (2008) Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization

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Retatrutide appears to produce the fastest weight loss trajectory, with participants in Phase 2 trials losing 24.2% of body weight in just 48 weeks, a pace that outstrips semaglutide and tirzepatide over comparable timeframes