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In laboratory research settings, PT-141 is utilized as a reference compound in studies investigating receptor binding dynamics, peptide stability, and signaling pathway behavior

Body weight and adiposity models: In diet-induced obesity (DIO) mouse models, retatrutide demonstrated pronounced effects on body weight trajectories over multi-week observation periods compared with vehicle controls

[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Ali O, Mezes M, Balogh K, et al