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To ensure sufficient intake of vitamin B12, older individuals are recommended to obtain it from supplements or fortified foods, such as ready-to-eat breakfast cereals

Response: We acknowledge comments that cited the additional burden to calculate the count of allowed amounts used when calculating the median, 10th percentile, and 90th percentile allowed amounts, derived from EDI 835 ERA transaction data

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In mouse models of highfat dietinduced obesity, it treatment significantly reduced mRNA and protein expression of TNF, IL6, and other inflammatory factors in adipose tissue and decreased macrophage infiltration - a hallmark of adipose inflammation

Other adverse effects, including the risk of malignancy, cardiovascular disease and subsequent death, are higher in smokers than nonsmokers