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10.3390/molecules27144565 81 LiL.BraitehF

doi: 10.1038/s41420-023-01717-2

Open Access Maced J Med Sci

This seemingly small chemical modification brings profound functional changes: the acetylated thiol group is protected from oxidation and enzymatic breakdown, while the overall molecules lipophilicity is significantly enhanced, allowing it to cross biological membranes more easily