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A nutrient can be absorbed perfectly well, but still have poor bioavailability if: the liver uses a large portion immediately, the nutrient breaks down quickly in the bloodstream, it isnt stored properly, it cant enter cells efficiently, it isnt chemically active by the time it arrives, its used rapidly during stress, inflammation, or detoxification

E.HabtemariamS.DagliaM.SuredaA.et al (2015)

Preclinical Toxicology: Toxicity studies in rodents indicate that even high doses (e.g., 20 mg/kg) do not result in gross organ toxicity or lethality in the acute setting

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Most notably, Mohammadzadeh-Honarvar et al

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