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Por ello, se han investigado muchos mtodos de optimizacin, como la esterificacin de la D-carnitina para formar una sal interna y luego su reduccin por hidrogenacin e hidrlisis para obtener L-carnitina, el mtodo de oxidacin-reduccin para oxidar el grupo hidroxilo de la D-carnitina a un grupo carbonilo aquiral y luego reducirlo para obtener L-carnitina, la inmovilizacin del catalizador S-(Salen)Co(III) utilizado en la sntesis en varios polmeros para permitir su reutilizacin, la recuperacin y aprovechamiento de los residuos de la resolucin selectiva, y el uso de mtodos bioqumicos para encontrar epxido hidrolasas que realicen la resolucin quiral de la epiclorhidrina

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