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They amplify what's already there rather than replacing it

Conversely, CO-GHD patients tend to be less insulin-resistant than AO-GHD patients (84), and their IGF-I levels are generally lower than their AO-GHD counterparts due to relatively lower intra-portal insulin levels

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While these episodes typically appear out of the blue, exercise, stress, or certain foods and drugs (such as caffeine or other stimulants) sometimes trigger an episode

2022;23:13146 Zheng Y, Scow JS, Duenes JA, Sarr MG

The hydrophilic B-block segment is preferably polyethylene glycol (PEG) having an average molecular weight of between about 500 and 2200 Daltons