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The authors also observed decreased forearm insulin-stimulated glucose disposal (during the clamp) and elevated plasma glucose during the mixed meal challenge demonstrating insulin resistance [6]

2021, www.nejm.org/doi/full/10.1056/NEJMoa2032183 ++ Garvey, W

Therefore, identifying drugs or targets activating Shh signaling pathway may exert neuroprotective effects by inhibiting microglial activation and reducing inflammation following OGD/R injury or cerebral ischemic injury

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Rather than positioning a single solution