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A follow-up cohort study further demonstrated that this association is partly mediated by low-grade systemic inflammation, highlighting inflammation as a mechanistic link between chronic NSW and IBS risk 155

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there was no change in the CRP value at T=0 between the two groups, and at T=48 hours its value in the group with acute pancreatitis was two times higher (Wilcoxon rank sum test 1 sided, p=0.035)

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It helps to inhibit melanin production, which can lead to significant skin brightening and a reduction in hyperpigmentation, while regular treatment can improve overall skin texture as well