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For phosphoproteomic analyses, the basal level of phosphorylation was set as the vehicle + PBS (VP) group and the phosphoproteome compared to the vehicle + insulin (VI) phosphoproteome (representative of prediabetic insulin-resistant state), and cotadutide + insulin (CI) phosphoproteome (representative of improved hepatic insulin sensitivity (as assessed during clamp studies)) (Fig

NCS, nerve conduction studies

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This is precisely why a numeric comparison does not work when it is done directly, and why clinical judgement is also key