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Nathan, S

2012(3):Cd007176

GLP-1 Stickers public service announcement

10.1152/ajprenal.00394.2015 166

Classically, three metabolic alterations have been identified that contribute to the development of T2DM: 1) insulin resistance, 2) an eventual decrease in insulin secretion from pancreatic beta cells, and 3) an excess production of glucose from the liver