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How To Calculate Tirzepatide Units To determine the correct number of units: Units = (Desired Dose Concentration) 100 Example: Desired dose = 2.5 mg Concentration = 10 mg/mL Units = (2.5 10) 100 Units = 25 This formula works for tirzepatide, semaglutide, and many other medications administered with U-100 insulin syringes