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Moreover, there have been hypoglycemic agents such as SGLT-is have been proven to have direct renal benefits independent of glucose

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They were referring to a study by the Federal Drug Authority in USA who looked at the effectiveness of old drugs,, some as old as thirty years and found them still as good as new.The NHS take a different view

10.1038/s41467-019-10588-0 136 Parodi-RullnR.GhisoJ.CabreraE.RostagnoA.FossatiS