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Through dual mechanismsdirect suppression of RAAS overactivation and enhancement of neuroreflex pathwaysHS reduces renal norepinephrine, plasma renin, and circulating AngII levels, thereby decreasing left ventricular size and preserving ejection fraction (Li et al., 2018)
Conversion Deiodinase (D2) activity in gut lining
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10.1080/01904160009382105 J