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GLP-1 receptor agonist (RA) medications are highly effective for managing weight and blood sugar, but they can also disrupt digestive healthleading to discomfort, irregularity, and microbial imbalance

In a recent study published in the eClinicalMedicine , a group of researchers evaluated the association between Glucagon-like peptide-1 receptor agonists (GLP-1 RA) use and the risk of suicide or suicide attempt, accounting for psychiatric history and obesity

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Only one study compared GLP1-RAs [51]

Liraglutide (LEADER trial), semaglutide (SUSTAIN-6), and dulaglutide (REWIND trial) demonstrated significant reductions in major adverse cardiovascular events