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T-scores and Z-scores were calculated using the manufacturers reference ranges

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The marked enhancement of mTORC1 signaling by CHX was also observed in the control cells (Fig

Additionally, in phase 2 studies in people with MASH and liver fibrosis, survodutide not only significantly improved liver steatosis, but also led to histologic improvement of MASH without worsening fibrosis in 4362% of participants, versus 14% with placebo [41]

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