Dement Geriatr Cognit Disord (2020) 49(5):42334
Pharmaceutical companies like Novo Nordisk and Eli Lilly want it both ways and continue to develop patent thickets made up of every minor modification of its products in order to extend patent protection that will increase the possibility of delaying competition and lengthening their market monopoly.As a result of this patent abuse, companies can maintain higher prices for longer, which then yields maximum revenue and profit to further enrich shareholders, all while perpetuating health inequities
This has implications for how to design human albumin-fused biologics, as QMP engineering may ensure a long plasma half-life, increased target exposure, and enhanced efficacy, despite potential C-terminal cleavage post-administration
However, there is some evidence that acarbose and voglibose, a structural analog of miglitol in clinical development in Japan, reduces post-prandial hyperinsulinemia in glucose intolerant individuals [190][191]
Supplements suggest that they can do the same
Polyphenol-rich foods like berries, apples, asparagus, dark chocolate, and walnuts
