Risks and Interactions to Discuss With Your GP or Specialist Key risks include herbal supplements reducing hormonal contraceptive efficacy, GLP-1 agonists worsening gastrointestinal symptoms, and orlistat impairing fat-soluble vitamin absorption
4 Mixture implications clarified ED, PBT, vPvB classifications will trigger at 0.1% concentration thresholds in mixtures Expect immediate impact on classification, labelling, and SDS updates 5 Not just new entries Also includes: Revisions to existing Annex VI entries Alignment of hazard profiles across regulatory regimes If youre working with PFAS, phenols, flame retardants, or siloxanes this will hit
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