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Kunal Shah, an assistant professor in the division of endocrinology at the Rutgers Robert Wood Johnson Medical Center in New Brunswick, New Jersey

Berberine, a bioactive alkaloid derived from various plants, including Berberis species, has garnered significant attention as a nutraceutical agent due to its potential benefits in metabolic health

Glucagon-like peptide 1 agonists (GLP-1) and Gastric inhibitory polypeptide (GIP) have emerged as valuable therapeutic agents for managing obesity and type 2 diabetes

Common side effects may include: Mounjaros side effect profile is better established because it is licensed

c Performed significantly more poorly than comparator.

One significant finding is from the SELECT trial, which showed that long-term use of semaglutide in individuals with obesity but without diabetes led to a 20% reduction in major cardiovascular events and an average weight loss of 9.4%