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The SURMOUNT trials in patients without diabetes showed even greater weight loss, with the 15 mg dose producing an average loss of 20.9 percent of body weight at 72 weeks compared to 14.9 percent for semaglutide in similar populations

The FDAs shortage list status for semaglutide has fluctuated, and the salt form controversy continues to work its way through the courts

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This gradual escalation helps minimise gastrointestinal side effects whilst allowing the body to adapt to the medication's appetite-modulating effects

Was the FDA decision final on 21 July 2026