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EstroGel Side Effects to Know Below are the reported possible side effects of EstroGelthe first two were the most common in clinical trials, and the others are listed in the FDA-approved patient info: headache breast tenderness or pain irregular vaginal bleeding or spotting stomach/abdominal cramps, bloating nausea and vomiting hair loss fluid retention vaginal yeast infection skin irritation at the application site Risks, Precautions, and Who May Not Be a Good Candidate EstroGel is generally well tolerated , but people with certain health histories or symptoms may not be a good candidate for it

Signs and symptoms may manifest in infants but often also appear in adolescents or adults during times of increased metabolic demand, such as fasting, physiologic stress, and prolonged exercise

Dosing in combination animal studies typically used ranges similar to monotherapy for each agent

PMID 16710915

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