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After menopause, estrogen levels drop sharply, leading to: Increased osteoclast activity Accelerated bone resorption Rising urinary DPD levels This makes DPD testing particularly valuable for postmenopausal women , helping identify those at highest risk for rapid bone loss

These data suggest progesterone-based therapies might constitute novel antiarrhythmic approaches in female LQTS patients

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Furthermore, liraglutide suppressed DNA fragmentation and the activity of matrix metalloproteinases-2 (MMP-2) and 9(MMP-9), while upregulating superoxide dismutase and IL-10 in the sciatic nerve [12]