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What Studies Show About Muscle Loss on GLP-1 Drugs The evidence on lean mass loss during GLP-1 therapy comes from the same large clinical trials that established these drugs as effective for weight loss

An Y, Lin S, Tan X, et al

Cell 185 , 24782494.e2428 (2022)

Reconstitution math, dose ranges, approval status, and evidence depth differ for each

Sudden weight reduction or maladaptation to an altered body perception may elicit biological and psychological reactions that can potentially impact suicidal thoughts