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NSAIDs can increase the risk of gastrointestinal irritation, which may compound existing GI side effects from tirzepatide including constipation and nausea

Tirzepatide (which also activates GIP receptors) may show slightly slower regain in early research, but long-term comparative data is limited

Between 2019 and 2024, prescriptions for GLP-1 drugs rose 587%

GLP-1 is a hormone that occurs naturally in the body

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