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In a 2015 review in BioMed Research International , Pickart, Vasquez-Soltero and Margolina collated Connectivity Map data showing GHK modulates expression of roughly 31 percent of profiled human genes in cultured fibroblasts

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The combined inflammatory impact of cytotoxicity by CD8+ T cells, immune-mediated perturbations of the islet ECM, and other mechanistic changes lead to cell death and decreased cell mass in a time-dependent manner ( Figure 2 )

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