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Besides being a channel blocker, amlodipine has been shown to have highly efficient antioxidant properties due to high lipophilicity and the ability to quench free radical formation (21)

We also cover the STOMP trial (do statins actually impair strength gains?), the SAMSON trial (how much of statin intolerance is nocebo?), the difference between myalgia, myositis, and rhabdomyolysis, Austins clinical approach to a patient whose strength is declining on a statin, and the treatment escalation pathway for statin-intolerant patients including bempedoic acid, PCSK9 inhibitors, and inclisiran

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Exercise-induced ROS generation can alter this sequence (Figure 1)