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Furthermore, exendin-4 administration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in vivo animal model of PD has been shown to inhibit microglial activation thereby minimizing the loss of dopaminergic neurons in the pars compacta of the substantia nigra and the striatum [78]

PUFAs are added to phospholipids (PLs) via the esterification action of long-chain fatty acid CoA ligase 4 (ACSL4), which enters the membrane to generate PUFA-PLs

The larger the point was, the more metabolites were enriched into this pathway

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Individual health status, medications, and underlying conditions should always be considered