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Clinical Trial Efficacy Data The approval is backed by two pivotal Phase 3 trials within the CORALreef clinical program evaluated at week 24: CORALreef Lipids Trial: Achieved a statistically significant 56% placebo-adjusted reduction in LDL-C (with a post-hoc analysis showing a 60% reduction when biological inconsistencies were removed)

These are puncture-resistant and leak-proof

Cells (2022) 11(16):2587

Which Indications Will Be Filed First

Methods This analysis mapped ICD-10 codes to the clinical criteria specified by CMS for the Medicare GLP-1 Bridge and utilized the 2023 20% Research Identifiable File (RIF) Medicare Fee-For-Service Claims and Medicare Advantage Encounter Data to create condition flags, along with the Part D Prescription Drug Event data to create a flag for GLP-1 use