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Semaglutide is used to treat type 2 diabetes and assist with weight loss

However, retatrutide is still investigational, tirzepatide has longer real-world experience, and side effects may be slightly more pronounced with retatrutide due to the triple-agonist mechanism

Retatrutide Retatrutide is a synthetic triple receptor agonist developed by Eli Lilly that simultaneously activates three receptors: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and the glucagon receptor

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Understanding GLP-1s: What It Is and How It Works What is GLP-1

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