Strength & Fitness Programmes: Tailored plans to help preserve muscle mass and improve overall health
doi:10.4103/1735-3327.166169 Cascella R, Evangelisti E, Zampagni M, et al
Because the cleavage activity of DPP-4 is depending on the presence of a penultimate Pro or Ala at the N-terminus, analogs of GLP-1 with substitutions at this position should be protected, and analogs with Ser, Val, or alpha-aminobutyric acid remained biologically active (104), so this problem could easily be solved, but the substitutions only increased the half-life from 1.5 to 45 min (104), the reason being a rapid extraction of GLP-1 in the kidneys (105), and probably also other enzymatic attacks (106)
USA 90 , 52925296 (1993)
Thomas Greiner PhD from the University of Gothenburg (Sweden), speaking about the various functions of GLP-1 in the gut, and the role of gut microbes in GLP-1 production, with ultimate effects on host health
He earned his bachelor's degree in psychology from Wheaton College and his Doctor of Pharmacy degree from the University of Minnesota
