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Diarrhea is the most common side effect

For example, administration of leptin into the ventral hippocampus decreases food intake [169], while that of ghrelin increases food intake [170]

Side effects from peptide medications reflect individual metabolic variation, genetic predispositions, and dosing protocols

However, it is worth noting that these studies employ model spaces that do not include an acceptance bias parameter, limiting comparability and posing the question whether association between dopaminergic signalling and reward sensitivity reflects a true computational specificity, or is instead a consequence of a constrained model space

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Regular physical activity, preferably earlier in the day, can promote better sleep quality and supports weight management goals