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[8] - [11] Neuromodulatory DSIP could help to compensate pathological metabolic damage in various animal species and humans, that is caused by oxygen deprivation in the body, preserving normal mitochondrial function and protecting tissue until proper blood flow is restored

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Gastrointestinal effects are among the most commonly reported adverse reactions to berberine in adults, including diarrhoea, constipation, abdominal pain, and nausea

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Lifestyle changes, including increased exercise, weight management, a healthier diet, stress management, and quitting smoking, may improve ED symptoms