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"They've gone on and off of diets [in the past], and it feels like maybe that's a history of restriction," Wiseman says, "and it feels really exciting to be able to continue to eat what they want and just have less." With their hunger suppressed by the medication, some will skip meals only to load up later on richer foods that can cause side effects like nausea, vomiting or constipation

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Longer-term ALC administration was not feasible due to resource constraints