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A meta-analysis found a 14% death rate in these cases, and a 2025 JAMA Network Open study showed that infection risk jumps sharply after day 3 of catheter use, with an adjusted odds ratio of 13.55

It does lead to some weight loss, around 4 kg at the 14 mg dose, but far less than Wegovy

For patients who find 12mg intolerable, stepping back to 8mg provides most of the benefit with better tolerability

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The drawbacks of GLP-1 medications It may seem like everyone is taking GLP-1 agonists