Yes, Contrave can cause an increase in blood pressure and heart rate, which is why it should not be used by people with uncontrolled hypertension
In addition to its use in diabetes management, semaglutide has also been FDA-approved for weight loss in individuals with obesity
They both commonly cause gastrointestinal side effects, such as nausea, vomiting, diarrhea, constipation, indigestion, gas, and stomach pain
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85% of the participants who took the semaglutide tablet lost at least 5% of their body weight compared to just 26% of those who took the placebo
MT2 produces faster, more pronounced pigmentation in most users at lower absolute doses, but this comes with a broader receptor activation profile that causes more side effects