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While Ex4 mildly reduced morphine-induced hyperlocomotion, it did not attenuate the expression of morphine-induced CPP, indicating a lack of effect on opioid reward in this model

An inverse association between cognitive decline and the ratio of w-3 to w-6 fatty acids in erythrocytes has been reported as well.10 Furthermore, increased fish and DHA intake were also found to be protective against cognitive decline and the risk of developing Alzheimer disease.11-14 Similarly, in our study, a 50% reduction in the risk of Alzheimer disease was associated with the consumption of more than 2 servings of fish per week