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I think nervous system health is very underappreciated wrt longevity and healthspan and that this hypothesis will largely be born out: Daniel Tawfik on X: "The hallmarks of aging describe what aging looks like at the molecular level

Diabetes mellitus: a cardiovascular disease

Mild dehydration can also mask true hunger cues or make it difficult to distinguish between nausea from the medication versus dehydration-related discomfort

Enhanced Metabolic Health : Significant improvements in blood sugar control, blood pressure, cholesterol profiles, and inflammation indicators are common among patients

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Tirzepatide availability Tirzepatide has been FDA-approved and available since 2022 for type 2 diabetes (as Mounjaro) and since 2023 for weight management (as Zepbound)