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In mice, raising BHB levels (either by fasting or administering exogenous ketones) protected against kidney IR injury and reduced IL-1 levels (123)

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Then ZFP and ZFPG (100 g mL 1 ) solution dispersed in the F12K medium was replaced with the previous medium and incubated for 24 h

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The combination therapy approaches detailed in PMC articles have reported manageable side effects consistent with those known for the individual drugs