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In cancer, CDO has been shown to divert the flow of cysteine away from glutathione synthesis, thereby promoting the production of ROS
Functionally, Dihexa was found to induce spinogenesis and synaptogenesis in hippocampal neurons at picomolar concentrations, indicating its ability to augment synaptic connectivity [2]
It is contraindicated in patients with an estimated glomerular filtration rate (eGFR) below 30 mL/min/1.73 m, should not be initiated in patients with an eGFR between 30-45 mL/min/1.73 m, and requires at least annual monitoring of renal function
It may also help to use a gentle cleanser before applying GHK-Cu and follow it with a basic, noncomedogenic moisturizer
Deeply hydrates while repairing the skin barrier
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