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In Australia, these drugs are popular for managing obesity and diabetes, but knowing the contraindications helps ensure they're used appropriately

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Therapeutics with enhanced efficacy, improved pharmacokinetics (PK) allowing less-frequent dosing and good tolerability remain in high demand to address the unmet medical need of patients with obesity

Moreover, melatonin-treated virulent pathogens exhibit disrupted spore structure, disturbance in cellular ultrastructure and increased mortality which reduces the disease severity in melatonin-treated host plants [169]