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Born in San Giovanni, Italy, Orci completed his medical training at Rome University and then gained a position at the Institute of Histology and Embryology at the University of Geneva in 1966

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18, 19, 65, 66 Given that both carnitine deficiency and PPA can be detrimental to mitochondrial metabolism, it is possible that antibiotic overuse can cause these two effects to act synergistically to cause an acquired mitochondrial disorder, especially in genetically susceptible individuals