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Critically, BPC-157 alone produced no behavioral or temperature effects, confirming it acts only when the serotonin system is disturbed

Transmission electron microscopy (TEM) imaging of OsO 4 -postfixed HEK293T cells showed that surface LaccID provides excellent contrast at the plasma membrane, with minimal staining of intracellular membranes on the ER, mitochondria and nucleus (Fig

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The critical role of the redox-sensitive transcription factor Nrf2 is highlighted by findings that Nrf2-deficient mice exhibit increased susceptibility to prolonged, noise-induced tinnitus-like behavior, accompanied by heightened microglial activation and neuroinflammation (Yang et al., 2025)

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