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(1999) Double-blind test on the efficacy of methylcobalamin on sleep-wake rhythm disorders

Despite the fact there's no evidence and real potential harm

On the other hand, those with severe kidney problems taking high amounts of B12 may see a high level of toxicity since the excess vitamin B12 wont get eliminated from the body easily

After 2-3 weeks of 250 mcg daily dosing, many patients increase to 500 mcg daily based on response and tolerance

If youre dangerously low on this vitamin, an injection allows us to administer a more controlled dose to help return you to normal levels

Best practice is to refrigerate after opening