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Cell-mediated immunity primarily needs protein antigen degradation in the endocytic vesicles of antigen presenting cells (macrophages, dendritic cells), to be able to present smaller peptides on the cell surface through major histocompatibility complex antigens to activate antigen-specific T cell proliferation

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In recent years, rapid advancements in ferroptosis research have led to the discovery of many effective ferroptosis regulators for clinical applications, and these discoveries have opened new avenues for treating ferroptosis-related diseases, with some showing promising clinical prospects

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