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For Concentrations often range from 1-10 M (micromolar)

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Individuals with Leber's hereditary optic neuropathy should avoid cyanocobalamin formulations, as there is evidence suggesting potential harm

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Genetic proof-of-concept Kraus et al

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As a result, B12 injections give new life to PA patients who would otherwise decline day after day until the disease killed them

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Conflict of interest The authors have no conflict of interest to declare.

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