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Blood Rev 2007;21:113-30

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Blher M., Rosenstock J., Hoefler J., Manuel R., Hennige A.M

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Cells were incubated with the ROS indicator, DCFH-DA, a membrane-permeable compound that becomes fluorescent upon intracellular esterase-mediated hydrolysis, yielding DCFH

-glutaredoxin upregulated the expression of the Nrf2 pathway and its downstream enzymes (CAT, SOD), enhanced endogenous antioxidant defence, increased GSH levels and reduced ROS accumulation [125]