Challenges and complications of poly(lactic- co -glycolic acid)-based long-acting drug product development
10.1016/j.redox.2021.102143 136 WangM.LiS.WangY.ChengH.SuJ.LiQ
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During this phase, matrix metalloproteinases (MMPs), primarily MMP7 , 10 and 11 , play a critical role in the degradation of the extracellular matrix (ECM) resulting in loss of structural integrity and tissue breakdown [11, 12] (Fig
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