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Polymeric nanomaterials such as poly(lactic acid) or polylactide-co-glycolide (PLGA) have ester bonds which undergo hydrolysis at the lower pH to release the cargoes, while co-block polymers containing boronic acid moieties possess altered solubility in acidic environment
USA 115 , E4061E4070 (2018)
Although the cancer mortality rate has decreased in recent years, access to healthcare has also decreased due to the COVID-19 pandemic, which has led to hampered cancer diagnosis and treatment (Siegel et al., 2021)
Abstract Leishmaniasis remains a significant global health challenge, with over a billion people at risk of infection and limited effective treatment options due to escalating drug resistance
10.1038/ejhg.2015.112 11 AshrafS.GeeH
But a spokesperson for Novo Nordisk has this week told The Pharmacist that while it has increased production, this will take time to take effect, and that it therefore envisaged intermittent supply shortages over the next 18 months
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